What is the primary pilot KPI for a CRO or Phase 1 site?

Query reduction. In Phase 1 oncology, every lab and every symptom can become a monitor query. When the grade lands in the EDC with the source sentence, the CTCAE criterion, the rationale, and the attribution support already attached, avoidable queries drop. Secondary metrics: EDC completeness, sponsor review turnaround, time to database lock.